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Target
Hypoxia-inducible factor 1-alpha inhibitor
Ligand
BDBM26108
Substrate
n/a
Meas. Tech.
ChEMBL_754093 (CHEMBL1798571)
Ki
83000±n/a nM
Citation
 Lohse, B; Kristensen, JL; Kristensen, LH; Agger, K; Helin, K; Gajhede, M; Clausen, RP Inhibitors of histone demethylases. Bioorg Med Chem 19:3625-36 (2011) [PubMed]  Article 
Target
Name:
Hypoxia-inducible factor 1-alpha inhibitor
Synonyms:
FIH1 | HIF1AN | HIF1N_HUMAN | Hypoxia-inducible factor 1 (FIH) | Hypoxia-inducible factor 1-alpha inhibitor
Type:
Enzyme
Mol. Mass.:
40278.92
Organism:
Homo sapiens (Human)
Description:
Q9NWT6
Residue:
349
Sequence:
MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
  
Inhibitor
Name:
BDBM26108
Synonyms:
(2R)-2-(formamidoformic acid)-4-phenylbutanoic acid | N-Oxalyl-D-homophenylalanine, 1c
Type:
Small organic molecule
Emp. Form.:
C12H13NO5
Mol. Mass.:
251.2353
SMILES:
OC(=O)[C@@H](CCc1ccccc1)NC(=O)C(O)=O |r|
Structure:
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