Reaction Details Report a problem with these data
Target
UDP-glucuronosyltransferase 1A7
Ligand
BDBM50206509
Substrate
n/a
Meas. Tech.
ChEMBL_774123 (CHEMBL1908128)
Ki
96000±n/a nM
Citation
 Kiang, TK; Ensom, MH; Chang, TK UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther 106:97-132 (2005) [PubMed]  Article 
Target
Name:
UDP-glucuronosyltransferase 1A7
Synonyms:
GNT1 | UD17_HUMAN | UDP-glucuronosyltransferase 1-7 | UDP-glucuronosyltransferase 1-G | UDP-glucuronosyltransferase 1A7 | UDPGT 1-7 | UGT-1G | UGT1 | UGT1*7 | UGT1-07 | UGT1.7 | UGT1A7 | UGT1G
Type:
PROTEIN
Mol. Mass.:
59829.76
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1489264
Residue:
530
Sequence:
MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
  
Inhibitor
Name:
BDBM50206509
Synonyms:
4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfamoyl-benzoic acid anion | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | Benemid | CHEMBL897 | PROBENECID | Probalan
Type:
Small organic molecule
Emp. Form.:
C13H19NO4S
Mol. Mass.:
285.359
SMILES:
CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Structure:
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