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Target
14-3-3 protein sigma
Ligand
BDBM50356015
Substrate
n/a
Meas. Tech.
ChEMBL_775356 (CHEMBL1912841)
Kd
>1000±n/a nM
Citation
 Corradi, V; Mancini, M; Santucci, MA; Carlomagno, T; Sanfelice, D; Mori, M; Vignaroli, G; Falchi, F; Manetti, F; Radi, M; Botta, M Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3s case. Bioorg Med Chem Lett 21:6867-71 (2011) [PubMed]  Article 
Target
Name:
14-3-3 protein sigma
Synonyms:
1433S_HUMAN | Epithelial cell marker protein 1 | HME1 | SFN | Stratifin
Type:
PROTEIN
Mol. Mass.:
27757.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_775356
Residue:
248
Sequence:
MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQEPQS
  
Inhibitor
Name:
BDBM50356015
Synonyms:
CHEMBL1911376
Type:
Small organic molecule
Emp. Form.:
C20H21N3O8
Mol. Mass.:
431.396
SMILES:
CCCCCCOC(=O)c1ccc(Nc2c(cc(cc2[N+]([O-])=O)C(O)=O)[N+]([O-])=O)cc1
Structure:
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