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Target
Proton-coupled amino acid transporter 1
Ligand
BDBM50038178
Substrate
n/a
Meas. Tech.
ChEMBL_788189 (CHEMBL1919336)
Ki
4400000±n/a nM
Citation
 Thondorf, I; Voigt, V; Schäfer, S; Gebauer, S; Zebisch, K; Laug, L; Brandsch, M Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem 19:6409-18 (2011) [PubMed]  Article 
Target
Name:
Proton-coupled amino acid transporter 1
Synonyms:
PAT1 | Proton/amino acid transporter 1 | S36A1_HUMAN | SLC36A1 | Solute carrier family 36 member 1 | hPAT1
Type:
PROTEIN
Mol. Mass.:
53078.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_788189
Residue:
476
Sequence:
MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI
  
Inhibitor
Name:
BDBM50038178
Synonyms:
(+)-4-Amino-3-isoxazolidinone | (4R)-4-aminoisoxazolidin-3-one | (R)-4-AMINO-ISOXAZOLIDIN-3-ONE | CHEMBL771 | D-CYCLOSERINE | alpha-Cycloserine | cycloserine
Type:
Small organic molecule
Emp. Form.:
C3H6N2O2
Mol. Mass.:
102.0919
SMILES:
N[C@@H]1CON=C1O |r,c:4|
Structure:
Search PDB for entries with ligand similarity: