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Target
3-phosphoshikimate 1-carboxyvinyltransferase
Ligand
BDBM50283584
Substrate
n/a
Meas. Tech.
ChEMBL_64948 (CHEMBL675693)
IC50
3000000±n/a nM
Citation
 Miller, MJ; Braccolino, DS; Clearly, DG; Ream, JE; Walker, MC; Sikorski, JA EPSP synthase inhibitor design IV. New aromatic substrate analogs and symmetrical inhibitors containing novel 3-phosphate mimics. Bioorg Med Chem Lett 4:2605-2608 (1994)    Article 
Target
Name:
3-phosphoshikimate 1-carboxyvinyltransferase
Synonyms:
5-enolpyruvylshikimate-3-phosphate synthase | AROA_ECOLI | aroA
Type:
PROTEIN
Mol. Mass.:
46089.22
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_65087
Residue:
427
Sequence:
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
  
Inhibitor
Name:
BDBM50283584
Synonyms:
CHEMBL88887 | disodium hydrogen 3-carboxy-5-[(hydroxyphosphinato)methyl]benzylphosphonate
Type:
Small organic molecule
Emp. Form.:
C9H10O8P2
Mol. Mass.:
308.1195
SMILES:
OC(=O)c1cc(CP(O)([O-])=O)cc(CP(O)([O-])=O)c1
Structure:
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