Reaction Details Report a problem with these data
Target
Protein tyrosine phosphatase receptor type C-associated protein
Ligand
BDBM50083572
Substrate
n/a
Meas. Tech.
ChEBML_210870
IC50
5300±n/a nM
Citation
 Miski, M; Xing, Shen; Cooper, R; Gillum, AM; Fisher, DK; Miller, RW; Higgins, TJ Aporphine alkaloids, CD45 protein tyrosine phosphatase inhibitors, from Rollinia ulei Bioorg Med Chem Lett 5:1519-1522 (1995)    Article 
Target
Name:
Protein tyrosine phosphatase receptor type C-associated protein
Synonyms:
CD45-AP | CD45-associated protein | LPAP | Lymphocyte phosphatase-associated phosphoprotein | PTCA_HUMAN | PTPRC-associated protein | PTPRCAP
Type:
PROTEIN
Mol. Mass.:
21182.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_210870
Residue:
206
Sequence:
MALPCTLGLGMLLALPGALGSGGSAEDSVGSSSVTVVLLLLLLLLLATGLALAWRRLSRDSGGYYHPARLGAALWGRTRRLLWASPPGRWLQARAELGSTDNDLERQEDEQDTDYDHVADGGLQADPGEGEQQCGEASSPEQVPVRAEEARDSDTEGDLVLGSPGPASAGGSAEALLSDLHAFAGSAAWDDSARAAGGQGLHVTAL
  
Inhibitor
Name:
BDBM50083572
Synonyms:
(S)-1,2-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | CHEMBL325416
Type:
Small organic molecule
Emp. Form.:
C18H19NO2
Mol. Mass.:
281.349
SMILES:
COc1cc2CCN[C@H]3Cc4ccccc4-c(c1OC)c23
Structure:
Search PDB for entries with ligand similarity: