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Target
Adenosine transporter 1
Ligand
BDBM50089708
Substrate
n/a
Meas. Tech.
ChEBML_31141
Ki
580±n/a nM
Citation
 Soulère, L; Hoffmann, P; Bringaud, F; Périé, J Synthesis and uptake of nitric oxide-releasing drugs by the P2 nucleoside transporter in Trypanosoma equiperdum. Bioorg Med Chem Lett 10:1347-50 (2000) [PubMed]  Article 
Target
Name:
Adenosine transporter 1
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
51044.02
Organism:
Trypanosoma brucei
Description:
ChEMBL_31141
Residue:
463
Sequence:
MLGFDSANEFIVYVTFLFFGMSVVVVTNSIFSMPFFFIEYYKYAQGKPDAKPEDPKFWKHMFTYYSIAAFLVELVLASLMLTPIGRRISVTVRLGVGLVIPIVLVFSVMMVTIVTTTETGAKVTIMLIAIANGVAMTLCDAGNAALIAPFPTKFYSSVVWGIAVCGVVTSFFSIVIKASMGGGYHNMLIQSRIYFGLVMFMQVISCALLVLLRKNPYAQKYAAEFRYAARKGIDDKGADGDEGNGAAKGPADQDDDPHGGDDTDKGNVMTATVDPDTMKDMDQVENITTSQQMLMARVWNVFWRVWPMLFACFMVFFTTFLVYPAVYFAIKADTGDGWYLTIAAALFNLGDFLSRLCLQFKALHVSPRWVLIGTFARMLLIIPLVLCVRSIITGPWLPYILVHAWGFTYGYYGGISQIYAPRTGSLTTAGERSLAANWTIISLLGGIFVGAMFALAVNEGLPK
  
Inhibitor
Name:
BDBM50089708
Synonyms:
2-(acetylamino)-N-{4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl}-3-methyl-3-(nitrosothio)butanamide | CHEMBL27357
Type:
Small organic molecule
Emp. Form.:
C16H21N9O3S
Mol. Mass.:
419.461
SMILES:
CC(=O)NC(C(=O)Nc1ccc(Nc2nc(N)nc(N)n2)cc1)C(C)(C)SN=O
Structure:
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