Reaction Details Report a problem with these data
Target
Adenosylhomocysteinase
Ligand
BDBM82524
Substrate
n/a
Meas. Tech.
ChEBML_196565
Ki
104700±n/a nM
Citation
 Steere, JA; Sampson, PB; Honek, JF Synthesis of an alpha-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase. Bioorg Med Chem Lett 12:457-60 (2002) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
Adenosylhomocysteinase | Ahcy | SAHH_RAT
Type:
PROTEIN
Mol. Mass.:
47537.52
Organism:
Rattus norvegicus
Description:
ChEMBL_1507790
Residue:
432
Sequence:
MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY
  
Inhibitor
Name:
BDBM82524
Synonyms:
5'-Deoxy-5'-isobutylthioadenosine | 5'-ISOBUTYLTHIO-5'-DEOXYADENOSINE | CAS_35899-54-8
Type:
Small organic molecule
Emp. Form.:
C14H21N5O3S
Mol. Mass.:
339.413
SMILES:
CC(C)CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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