Reaction Details Report a problem with these data
Target
Adenosine deaminase
Ligand
BDBM50226311
Substrate
n/a
Meas. Tech.
ChEMBL_31101 (CHEMBL640457)
Ki
1000±n/a nM
Citation
 Kim, CH; Marquez, VE; Mao, DT; Haines, DR; McCormack, JJ Synthesis of pyrimidin-2-one nucleosides as acid-stable inhibitors of cytidine deaminase. J Med Chem 29:1374-80 (1986) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA_MOUSE | Ada
Type:
PROTEIN
Mol. Mass.:
39984.63
Organism:
Mus musculus
Description:
ChEMBL_31100
Residue:
352
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ
  
Inhibitor
Name:
BDBM50226311
Synonyms:
CHEBI:46938 | Zebularine
Type:
Small organic molecule
Emp. Form.:
C9H12N2O5
Mol. Mass.:
228.202
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cccnc1=O |r|
Structure:
Search PDB for entries with ligand similarity: