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Target
Adenosylhomocysteinase
Ligand
BDBM50029130
Substrate
n/a
Meas. Tech.
ChEMBL_197369 (CHEMBL800622)
IC50
40±n/a nM
Citation
 Madhavan, GV; McGee, DP; Rydzewski, RM; Boehme, R; Martin, JC; Prisbe, EJ Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem 31:1798-804 (1988) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50029130
Synonyms:
Adenosine dialdehyde | CHEMBL165876
Type:
Small organic molecule
Emp. Form.:
C10H11N5O4
Mol. Mass.:
265.2254
SMILES:
Nc1ncnc2n(cnc12)[C@H](O[C@H](CO)C=O)C=O
Structure:
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