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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50005677
Substrate
n/a
Meas. Tech.
ChEMBL_98894 (CHEMBL703402)
Ki
0.780000±n/a nM
Citation
 Trybulski, EJ; Zhang, J; Kramss, RH; Mangano, RM The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives. J Med Chem 36:3533-41 (1994) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50005677
Synonyms:
CHEMBL23957 | OXO-M | Trimethyl-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-ammonium; iodide
Type:
Small organic molecule
Emp. Form.:
C11H19N2O
Mol. Mass.:
195.2808
SMILES:
C[N+](C)(C)CC#CCN1CCCC1=O
Structure:
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