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Target
Phosphodiesterase
Ligand
BDBM23620
Substrate
n/a
Meas. Tech.
ChEBML_155849
IC50
>100000±n/a nM
Citation
 Takase, Y; Saeki, T; Fujimoto, M; Saito, I Cyclic GMP phosphodiesterase inhibitors. 1. The discovery of a novel potent inhibitor, 4-((3,4-(methylenedioxy)benzyl)amino)-6,7,8-trimethoxyquinazoline. J Med Chem 36:3765-70 (1994) [PubMed]  Article 
Target
Name:
Phosphodiesterase
Synonyms:
Phosphodiesterase 3A
Type:
PROTEIN
Mol. Mass.:
108833.33
Organism:
Sus scrofa
Description:
ChEMBL_155977
Residue:
985
Sequence:
MGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGVGEDHLLSLPAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYLAYLAGVLGILLARYVEQILPQSAGAAPREHFGSQLLAGTKEDIPEFKRRRRSSSVVSAEMSGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPAVSFSENYTCSDSEESAEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPSPVRRDRSASIKLHEAPSSSAINPDSWKNPVMMTLTKSRSFTSSYAVSASNHVKAKKQSRPGSLVKISPLSSPCSSALQGTPASSPVSKISTVQFPEPADATAKQGLSSHKALTYTQSAPDLSPHILTPPVICSSCGRPYSQGNPADGPLERSGPAIQAQSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECSREPLRKASACSAYTPDTMMFLDKPILAPEPLVMDNLDSIMEHLNTWNFPIFDLVEKIGRKCGRILSQVSYRLFEDMGLFEAFKIPIREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGLSTVINDHGSTSDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRTEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNDEVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVEDSDESGDTDDPEEEEAPKEEETCENNDSPRKKTFKRRKIYCQITQHLLQNHKMWKKVIEEEQRLAGIESQSLDQAPQQHSSEQIQAIKEEDEDKGKPRGEETPTPKPNQ
  
Inhibitor
Name:
BDBM23620
Synonyms:
2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol | CHEMBL932 | Dipyridamine | Dipyridamole | Dipyudamine | MLS000028420 | Persantine | SMR000058382 | cid_3108
Type:
Small organic molecule
Emp. Form.:
C24H40N8O4
Mol. Mass.:
504.6256
SMILES:
OCCN(CCO)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCO)CCO
Structure:
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