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Target
Adenosine receptor A1
Ligand
BDBM50453656
Substrate
n/a
Meas. Tech.
ChEMBL_29762 (CHEMBL875506)
Ki
66300±n/a nM
Citation
 Jacobson, KA; Siddiqi, SM; Olah, ME; Ji, XD; Melman, N; Bellamkonda, K; Meshulam, Y; Stiles, GL; Kim, HO Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors. J Med Chem 38:1720-35 (1995) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50453656
Synonyms:
CHEMBL2113695
Type:
Small organic molecule
Emp. Form.:
C29H43ClIN5O5Si2
Mol. Mass.:
760.211
SMILES:
[H][C@@]12CO[Si](O[Si](O[C@@]1([H])[C@@H](O)[C@@H](O2)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc12)(C(C)C)C(C)C)(C(C)C)C(C)C |r|
Structure:
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