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Target
L-selectin
Ligand
BDBM50050500
Substrate
n/a
Meas. Tech.
ChEMBL_199999 (CHEMBL810688)
IC50
30000±n/a nM
Citation
 Wada, Y; Saito, T; Matsuda, N; Ohmoto, H; Yoshino, K; Ohashi, M; Kondo, H; Ishida, H; Kiso, M; Hasegawa, A Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders. J Med Chem 39:2055-9 (1996) [PubMed]  Article 
Target
Name:
L-selectin
Synonyms:
LNHR | LYAM1 | LYAM1_HUMAN | Leukocyte adhesion molecule-1 | SELL | Selectin
Type:
PROTEIN
Mol. Mass.:
42187.20
Organism:
Homo sapiens (Human)
Description:
ChEMBL_200000
Residue:
372
Sequence:
MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGKKSKRSMNDPY
  
Inhibitor
Name:
BDBM50050500
Synonyms:
CHEMBL3085443 | Sodium; 3,5-dihydroxy-2-[5-hydroxy-2-hydroxymethyl-6-(2-tetradecyl-hexadecyloxy)-4-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-4-sulfonate
Type:
Small organic molecule
Emp. Form.:
C48H91NaO17S
Mol. Mass.:
995.281
SMILES:
[Na+].CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)CO[C@@H]1O[C@@H](CO)[C@@H](O[C@@H]2O[C@@H](CO)[C@H](O)[C@@H]([C@@H]2O)S([O-])(=O)=O)[C@H](O[C@H]2O[C@@H](C)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H]1O |r|
Structure:
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