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Target
D(2) dopamine receptor
Ligand
BDBM84637
Substrate
n/a
Meas. Tech.
ChEMBL_62072 (CHEMBL672372)
Kd
1900±n/a nM
Citation
 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors. J Med Chem 43:3005-19 (2000) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM84637
Synonyms:
CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPIROLE | Quinpirole,(-) | US9359372, Quinpirole
Type:
Small organic molecule
Emp. Form.:
C13H21N3
Mol. Mass.:
219.3259
SMILES:
CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r|
Structure:
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