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Target
Adenosine transporter 1
Ligand
BDBM50105135
Substrate
n/a
Meas. Tech.
ChEMBL_149711 (CHEMBL755808)
Ki
135±n/a nM
Citation
 Klenke, B; Stewart, M; Barrett, MP; Brun, R; Gilbert, IH Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs. J Med Chem 44:3440-52 (2001) [PubMed]  Article 
Target
Name:
Adenosine transporter 1
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
51044.02
Organism:
Trypanosoma brucei
Description:
ChEMBL_31141
Residue:
463
Sequence:
MLGFDSANEFIVYVTFLFFGMSVVVVTNSIFSMPFFFIEYYKYAQGKPDAKPEDPKFWKHMFTYYSIAAFLVELVLASLMLTPIGRRISVTVRLGVGLVIPIVLVFSVMMVTIVTTTETGAKVTIMLIAIANGVAMTLCDAGNAALIAPFPTKFYSSVVWGIAVCGVVTSFFSIVIKASMGGGYHNMLIQSRIYFGLVMFMQVISCALLVLLRKNPYAQKYAAEFRYAARKGIDDKGADGDEGNGAAKGPADQDDDPHGGDDTDKGNVMTATVDPDTMKDMDQVENITTSQQMLMARVWNVFWRVWPMLFACFMVFFTTFLVYPAVYFAIKADTGDGWYLTIAAALFNLGDFLSRLCLQFKALHVSPRWVLIGTFARMLLIIPLVLCVRSIITGPWLPYILVHAWGFTYGYYGGISQIYAPRTGSLTTAGERSLAANWTIISLLGGIFVGAMFALAVNEGLPK
  
Inhibitor
Name:
BDBM50105135
Synonyms:
CHEMBL542936 | N2-(3-((12-((3-((4Amino,6-(methylamino)-1,3,5-triazin-2-yl)amino)propyl)amino)dodecyl)amino)-propyl)N4-methyl-1,3,5-triazine-4,2,6-triamine pentaahydrochloride
Type:
Small organic molecule
Emp. Form.:
C26H52N14
Mol. Mass.:
560.7849
SMILES:
CNc1nc(N)nc(NCCCNCCCCCCCCCCCCNCCCNc2nc(N)nc(NC)n2)n1
Structure:
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