Reaction Details Report a problem with these data
Target
Histone deacetylase 2b
Ligand
BDBM50115657
Substrate
n/a
Meas. Tech.
ChEMBL_87877 (CHEMBL697299)
IC50
40±n/a nM
Citation
 Miller, TA; Witter, DJ; Belvedere, S Histone deacetylase inhibitors. J Med Chem 46:5097-116 (2003) [PubMed]  Article 
Target
Name:
Histone deacetylase 2b
Synonyms:
Histone deacetylase HD2
Type:
PROTEIN
Mol. Mass.:
30785.07
Organism:
Zea mays
Description:
ChEMBL_87549
Residue:
286
Sequence:
MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVEKHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQNNEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEMSEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSEQSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
  
Inhibitor
Name:
BDBM50115657
Synonyms:
(S)-2-(7-Hydroxycarbamoyl-heptanoylamino)-3-naphthalen-2-yl-propionic acid methyl ester | 2-(7-Hydroxycarbamoyl-heptanoylamino)-3-naphthalen-2-yl-propionic acid methyl ester | CHEMBL113337
Type:
Small organic molecule
Emp. Form.:
C22H28N2O5
Mol. Mass.:
400.4681
SMILES:
COC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)CCCCCCC(=O)NO
Structure:
Search PDB for entries with ligand similarity: