Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50153977
Substrate
n/a
Meas. Tech.
ChEMBL_302809 (CHEMBL838517)
Ki
1500000±n/a nM
Citation
 Innocenti, A; Lehtonen, JM; Parkkila, S; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorg Med Chem Lett 14:5435-9 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50153977
Synonyms:
CHEMBL186537 | N3H | [NNNH] | hydrazoic acid | hydrido-1kappaH-trinitrogen(2N--N)hydrogen trinitride(1-) | hydrogen azide | triazoic acid
Type:
Small organic molecule
Emp. Form.:
HN3
Mol. Mass.:
43.028
SMILES:
N=[N+]=[N-]
Structure:
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