Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 20
Ligand
BDBM50206441
Substrate
n/a
Meas. Tech.
ChEMBL_508178 (CHEMBL1008236)
Ki
4400±n/a nM
Citation
 Kaler, G; Truong, DM; Khandelwal, A; Nagle, M; Eraly, SA; Swaan, PW; Nigam, SK Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem 282:23841-53 (2007) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 20
Synonyms:
Gm963 | Oat6 | S22AK_MOUSE | Slc22a20
Type:
PROTEIN
Mol. Mass.:
60953.19
Organism:
Mus musculus
Description:
ChEMBL_508178
Residue:
556
Sequence:
MAFTDLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEPTTNVSGVWLRAAIPLNQHGDPEPCRRYVEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEFASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVPLVETIAAMERRVKQGRSKRDTEQKSEEISLQQLGASPLKETI
  
Inhibitor
Name:
BDBM50206441
Synonyms:
2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate | CHEMBL376503
Type:
Small organic molecule
Emp. Form.:
C20H8Br4O5
Mol. Mass.:
647.891
SMILES:
OC(=O)c1ccccc1-c1c2cc(Br)c(O)c(Br)c2oc2c(Br)c(=O)c(Br)cc12 |(32.53,-16.69,;33.02,-15.23,;32,-14.07,;34.53,-14.92,;34.52,-13.38,;35.85,-12.6,;37.19,-13.36,;37.2,-14.9,;35.87,-15.67,;35.87,-17.21,;37.21,-17.96,;38.54,-17.19,;39.88,-17.94,;41.21,-17.16,;39.89,-19.5,;41.23,-20.26,;38.56,-20.28,;38.57,-21.82,;37.22,-19.51,;35.88,-20.29,;34.55,-19.52,;33.22,-20.3,;33.22,-21.84,;31.88,-19.53,;30.55,-20.3,;31.88,-17.98,;30.56,-17.2,;33.22,-17.24,;34.55,-17.98,)|
Structure:
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