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Target
Class A beta-lactamase BCL-1
Ligand
BDBM50021959
Substrate
n/a
Meas. Tech.
ChEMBL_521247 (CHEMBL1002558)
IC50
85±n/a nM
Citation
 Girlich, D; Leclercq, R; Naas, T; Nordmann, P Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii. Antimicrob Agents Chemother 51:4009-14 (2007) [PubMed]  Article 
Target
Name:
Class A beta-lactamase BCL-1
Synonyms:
Beta-lactamase
Type:
PROTEIN
Mol. Mass.:
33479.14
Organism:
Bacillus clausii
Description:
ChEMBL_521247
Residue:
307
Sequence:
MKRSFFMLKTKITSSILVGACLLIGCSNGNEQPVSNEPEPEESVETGEAVFKALEEEYAARLGVFALDTGTGQTVSYRSDERFTYASAHKPLAVAVLLQQKSIEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGPEGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQELLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSKDEKDAEYDDELIAKATEEVINLLAQTE
  
Inhibitor
Name:
BDBM50021959
Synonyms:
CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
Type:
Small organic molecule
Emp. Form.:
C8H9NO5
Mol. Mass.:
199.1608
SMILES:
OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure:
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