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Target
Glutathione reductase, mitochondrial
Ligand
BDBM50316592
Substrate
n/a
Meas. Tech.
ChEMBL_571638 (CHEMBL1031293)
Ki
11700±n/a nM
Citation
 Sentürk, M; Talaz, O; Ekinci, D; Cavdar, H; Küfrevioglu, OI In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates. Bioorg Med Chem Lett 19:3661-3 (2009) [PubMed]  Article 
Target
Name:
Glutathione reductase, mitochondrial
Synonyms:
GLUR | GRD1 | GSHR_HUMAN | GSR | Glutathione reductase | Glutathione reductase (GR)
Type:
Enzyme
Mol. Mass.:
56271.52
Organism:
Homo sapiens (Human)
Description:
P00390
Residue:
522
Sequence:
MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
  
Inhibitor
Name:
BDBM50316592
Synonyms:
(2R(S),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl nitrate | CHEMBL1094857
Type:
Small organic molecule
Emp. Form.:
C7H11NO4
Mol. Mass.:
173.1665
SMILES:
O[C@@H]1C2CCC1[C@@H](C2)O[N+]([O-])=O |r,THB:0:1:4.3:7.6|
Structure:
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