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Reaction Details
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TargetCruzipain
LigandBDBM50318910
Substrate/Competitorn/a
Meas. Tech.ChEMBL_635150
IC50>300000±n/a nM
Citation Doak, AKWille, HPrusiner, SBShoichet, BK Colloid formation by drugs in simulated intestinal fluid. J Med Chem53:4259-65 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cruzipain
Name:Cruzipain
Synonyms:Cruzain | Cruzaine | Major cysteine proteinase
Type:Protein
Mol. Mass.:49831.41
Organism:Trypanosoma cruzi
Description:P25779
Residue:467
Sequence:
MSGWARALLLAAVLVVMACLVPAATASLHAEETLTSQFAEFKQKHGRVYESAAEEAFRLS
VFRENLFLARLHAAANPHATFGVTPFSDLTREEFRSRYHNGAAHFAAAQERARVPVKVEV
VGAPAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDK
TDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL
PQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYW
IIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVGGPGPTPEPTTTTTTSAPGPSPSY
FVQMSCTDAACIVGCENVTLPTGQCLLTTSGVSAIVTCGAETLTEEVFLTSTHCSGPSVR
SSVPLNKCNRLLRGSVEFFCGSSSSGRLADVDRQRRHQPYHSRHRRL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50318910
NameBDBM50318910
Synonyms:CHEMBL1083385 | CLOPIDOGREL BISULFATE | Clopidogrel | SR-25990C | clopidogrel sulfate
TypeSmall organic molecule
Emp. Form.C16H16ClNO2S
Mol. Mass.321.822
SMILESCOC(=O)[C@@H](N1CCc2sccc2C1)c1ccccc1Cl |r|
Structure
n/a