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Target
Interleukin-5
Ligand
BDBM50354850
Substrate
n/a
Meas. Tech.
ChEMBL_642273 (CHEMBL1177153)
IC50
26200±n/a nM
Citation
Thanigaimalai, P; Lee, KC; Sharma, VK; Yun, JH; Kim, Y; Jung, SH Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity. Bioorg Med Chem 18:4625-9 (2011) [PubMed] Article
More Info.:
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
Inhibitor
Name:
BDBM50354850
Synonyms:
BUDESONIDE | US10869929, Compound Budesonide | US11554172, Compound Budesonide | US11760775, Compound Budesonide
Type:
Small organic molecule
Emp. Form.:
C25H34O6
Mol. Mass.:
430.5339
SMILES:
CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:15,t:11|