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Target
Solute carrier family 15 member 2
Ligand
BDBM50169128
Substrate
n/a
Meas. Tech.
ChEMBL_762551 (CHEMBL1817008)
Ki
23000±n/a nM
Citation
 Pedretti, A; De Luca, L; Marconi, C; Regazzoni, L; Aldini, G; Vistoli, G Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping. Bioorg Med Chem 19:4544-51 (2011) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 2
Synonyms:
Kidney H(+)/peptide cotransporter | Oligopeptide transporter, kidney isoform | PEPT2 | Peptide transporter 2 | S15A2_HUMAN | SLC15A2
Type:
PROTEIN
Mol. Mass.:
81795.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_762551
Residue:
729
Sequence:
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMIKLETKKTKL
  
Inhibitor
Name:
BDBM50169128
Synonyms:
(S)-1-[(S)-1-((S)-2-Amino-3-methyl-butyryl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid | CHEMBL190414
Type:
Small organic molecule
Emp. Form.:
C15H25N3O4
Mol. Mass.:
311.3767
SMILES:
CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)=O
Structure:
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