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Target
Regulator of G-protein signaling 8
Ligand
BDBM50384757
Substrate
n/a
Meas. Tech.
ChEMBL_821036 (CHEMBL2039223)
IC50
9900±n/a nM
Citation
 Turner, EM; Blazer, LL; Neubig, RR; Husbands, SM Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett 3:146-150 (2012) [PubMed]  Article 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM50384757
Synonyms:
CHEMBL2037354
Type:
Small organic molecule
Emp. Form.:
C17H16N2O2S
Mol. Mass.:
312.386
SMILES:
Cc1ccc(cc1)-n1sc(=O)n(Cc2cccc(C)c2)c1=O
Structure:
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