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Target
Regulator of G-protein signaling 8
Ligand
BDBM50384767
Substrate
n/a
Meas. Tech.
ChEMBL_821036 (CHEMBL2039223)
IC50
7700±n/a nM
Citation
 Turner, EM; Blazer, LL; Neubig, RR; Husbands, SM Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett 3:146-150 (2012) [PubMed]  Article 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM50384767
Synonyms:
CHEMBL2037365
Type:
Small organic molecule
Emp. Form.:
C13H16N2O2S
Mol. Mass.:
264.343
SMILES:
CC(C)Cn1c(=O)sn(-c2ccc(C)cc2)c1=O
Structure:
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