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TargetMu-type opioid receptor
LigandBDBM50386381
Substrate/Competitorn/a
Meas. Tech.ChEMBL_826808
EC50 670±n/a nM
Citation Renton, PGreen, BMaddaford, SRakhit, SAndrews, JS NOpiates: Novel Dual Action Neuronal Nitric Oxide Synthase Inhibitors with -Opioid Agonist Activity. ACS Med Chem Lett3:227-231 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50386381
NameBDBM50386381
Synonyms:Nucynta | TAPENTADOL HYDROCHLORIDE | Tapentadol
TypeSmall organic molecule
Emp. Form.C14H23NO
Mol. Mass.221.3385
SMILESCC[C@H]([C@@H](C)CN(C)C)c1cccc(O)c1
Structure
n/a