Reaction Details Report a problem with these data
Target
4,4'-diapophytoene synthase
Ligand
BDBM50388397
Substrate
n/a
Meas. Tech.
ChEMBL_829914 (CHEMBL2061562)
Ki
1500±n/a nM
Citation
 Lin, FY; Liu, YL; Li, K; Cao, R; Zhu, W; Axelson, J; Pang, R; Oldfield, E Head-to-head prenyl tranferases: anti-infective drug targets. J Med Chem 55:4367-72 (2012) [PubMed]  Article 
Target
Name:
4,4'-diapophytoene synthase
Synonyms:
CRTM_STAAU | Dehydrosqualene synthase | crtM
Type:
PROTEIN
Mol. Mass.:
34309.10
Organism:
Staphylococcus aureus
Description:
ChEMBL_1352846
Residue:
287
Sequence:
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
  
Inhibitor
Name:
BDBM50388397
Synonyms:
CHEMBL39581
Type:
Small organic molecule
Emp. Form.:
C15H13NO2S
Mol. Mass.:
271.334
SMILES:
N#CSCCOc1ccc(Oc2ccccc2)cc1
Structure:
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