Reaction Details Report a problem with these data
Target
Monocarboxylate transporter 2
Ligand
BDBM23446
Substrate
n/a
Meas. Tech.
ChEMBL_838262 (CHEMBL2076210)
IC50
14000±n/a nM
Citation
 Bröer, S; Bröer, A; Schneider, HP; Stegen, C; Halestrap, AP; Deitmer, JW Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. Biochem J 341:529-35 (1999) [PubMed]  Article 
Target
Name:
Monocarboxylate transporter 2
Synonyms:
MOT2_RAT | Mct2 | RCG59598, isoform CRA_b | Slc16a7 | Slc16a7 protein
Type:
PROTEIN
Mol. Mass.:
53065.35
Organism:
Rattus norvegicus
Description:
ChEMBL_838262
Residue:
489
Sequence:
MPSESSVKATAAPPPFPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSPRAAKSKSKVGSRQDSSTKRLSKVSTAEKINRFLDFGLFTHRGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVMAFTDMFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGIYLLICNAINYRLLEKERKREKARRKKSASQASKEMEALSRSKQDDVTVKVSNTHNPPSDRDKESSI
  
Inhibitor
Name:
BDBM23446
Synonyms:
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one | CHEMBL45068 | Phloretin | cid_4788
Type:
Dihydrochalcone
Emp. Form.:
C15H14O5
Mol. Mass.:
274.2687
SMILES:
Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
Structure:
Search PDB for entries with ligand similarity: