Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 7
Ligand
BDBM50390999
Substrate
n/a
Meas. Tech.
ChEMBL_835958 (CHEMBL2077096)
IC50
1620000±n/a nM
Citation
 Khamdang, S; Takeda, M; Babu, E; Noshiro, R; Onozato, ML; Tojo, A; Enomoto, A; Huang, XL; Narikawa, S; Anzai, N; Piyachaturawat, P; Endou, H Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. Eur J Pharmacol 465:1-7 (2003) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 7
Synonyms:
Nlt | Novel liver transporter | Oat2 | Organic anion transporter 2 | S22A7_RAT | Slc22a7
Type:
PROTEIN
Mol. Mass.:
58654.52
Organism:
Rattus norvegicus
Description:
ChEMBL_836967
Residue:
535
Sequence:
MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPANLSHQDLWLEAHLPRETDGSFSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNVVTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTEAGMLLGAALTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQDVERKSTQEEDV
  
Inhibitor
Name:
BDBM50390999
Synonyms:
CEFOPERAZONE
Type:
Small organic molecule
Emp. Form.:
C25H27N9O8S2
Mol. Mass.:
645.667
SMILES:
CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O |c:26|
Structure:
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