Reaction Details Report a problem with these data
Target
Solute carrier organic anion transporter family member 1A3
Ligand
BDBM17638
Substrate
n/a
Meas. Tech.
ChEMBL_837084 (CHEMBL2076336)
Ki
1000000±n/a nM
Citation
 Masuda, S; Saito, H; Inui, KI Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1. J Pharmacol Exp Ther 283:1039-42 (1998) [PubMed] 
Target
Name:
Solute carrier organic anion transporter family member 1A3
Synonyms:
OAT-K1 | OAT-K2 | Oatp1a3 | SO1A3_RAT | Slc21a4 | Slco1a3 | Sodium-independent organic anion transporter K1 | Solute carrier family 21 member 4 | rOAT-K
Type:
PROTEIN
Mol. Mass.:
73829.31
Organism:
Rattus norvegicus
Description:
ChEMBL_838743
Residue:
670
Sequence:
MGDLEKGAATHGAGCFAKIKVFLMALTCAYVSKSLSGTFMSSMLTQIERQFGIPTAIVGFINGSFEIGNLLLIIFVSYFGMKLHRPIVIGVGCAVMGLGCFIISLPHFLMGRYEYETTILPTSNLSSNSFLCMENQTQTLNPAQDPAECVKEVKSLMWIYVLVGNIIRGIGETPIMPLGVSYIENFAKSENSPLYIGILETGKMIGPIFGLLLGSFCASIYVDTGSVNTDDLTITPTDIRWVGAWWIGFLVCAGVNILISIPFFFFPKTLPKEGLQENVDGTENAKEESTEKRPRKKNRGITKDFFPFLKSPVLQPDLHAVHPYKVLQVNAFNIYFSFLPKYLENQYGKSTAEVIFLMGVYNLPAICIGYLIAGFMMKKFKITVKTAAFLAFCLSLSEYSFGFCNFLITCDNVPVAGLTNSYERDQKPLYLENNVLADCNTRCSCLTKTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFHNCSCIQSPGNSSAVLGLCNKGPECTNKLQYLLILSGFLSILYSFAAIPGYMVFLRCIKSEEKSLGIGIHAFCIRVFAGIPAPIYFGALIDRTCLHWGTQKCGAPGACRMYDINSFRRIYLGMSAALRGSSYLPAFVIVILTRKFSLPGKINSSEMEIAEMKLTEKESQCTDVHRNPKFKNDGELKTKL
  
Inhibitor
Name:
BDBM17638
Synonyms:
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid | CHEMBL6 | Indocin | Indomethacin | US11478464, Compound Indomethacin | US11786535, Compound Indomethacin | US9271961, Indomethacin | indometacin
Type:
Small organic molecule
Emp. Form.:
C19H16ClNO4
Mol. Mass.:
357.788
SMILES:
COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
Structure:
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