Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50366480
Substrate
n/a
Meas. Tech.
ChEMBL_873670 (CHEMBL2188786)
EC50
200±n/a nM
Citation
 Yelovitch, S; Barr, HM; Camden, J; Weisman, GA; Shai, E; Varon, D; Fischer, B Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist. J Med Chem 55:7623-35 (2012) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1_RAT | P2Y1 | P2ry1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
PROTEIN
Mol. Mass.:
42338.46
Organism:
Rattus norvegicus
Description:
ChEMBL_873671
Residue:
373
Sequence:
MTEVPWSAVPNGTDAAFLAGLGSLWGNSTIASTAAVSSSFRCALIKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGIRKNKTVTCYDSTSDEYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL
  
Inhibitor
Name:
BDBM50366480
Synonyms:
ADENOSINE TRIPHOSPHATE | ATP
Type:
Small organic molecule
Emp. Form.:
C10H16N5O13P3
Mol. Mass.:
507.181
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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