Reaction Details Report a problem with these data
Target
P2X purinoceptor 4
Ligand
BDBM50366480
Substrate
n/a
Meas. Tech.
ChEMBL_876875 (CHEMBL2184469)
EC50
1000±n/a nM
Citation
 Hernandez-Olmos, V; Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Weinhausen, S; Müller, CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem 55:9576-88 (2012) [PubMed]  Article 
Target
Name:
P2X purinoceptor 4
Synonyms:
ATP receptor | P2RX4_MOUSE | P2rx4 | P2x4 | Purinergic receptor
Type:
PROTEIN
Mol. Mass.:
43443.55
Organism:
Mus musculus
Description:
ChEMBL_1283887
Residue:
388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ
  
Inhibitor
Name:
BDBM50366480
Synonyms:
ADENOSINE TRIPHOSPHATE | ATP
Type:
Small organic molecule
Emp. Form.:
C10H16N5O13P3
Mol. Mass.:
507.181
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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