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Target
7-dehydrocholesterol reductase
Ligand
BDBM50406618
Substrate
n/a
Meas. Tech.
ChEMBL_53601 (CHEMBL665488)
Ki
12±n/a nM
Citation
 Ator, MA; Schmidt, SJ; Adams, JL; Dolle, RE; Kruse, LI; Frey, CL; Barone, JM Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase. J Med Chem 35:100-6 (1992) [PubMed]  Article 
Target
Name:
7-dehydrocholesterol reductase
Synonyms:
DHCR7_RAT | Dhcr7
Type:
PROTEIN
Mol. Mass.:
54168.97
Organism:
Rattus norvegicus
Description:
ChEMBL_53595
Residue:
471
Sequence:
MASKSQHNASKAKNHNVKAESQGQWGRAWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQYSCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF
  
Inhibitor
Name:
BDBM50406618
Synonyms:
CHEMBL9875
Type:
Small organic molecule
Emp. Form.:
C29H51N2O
Mol. Mass.:
443.7275
SMILES:
[#6]-[#6@H](-[#6]-[#6]\[#6](-[#7])=[#7+](/[#6])-[#6])-[#6]1-[#6]-[#6][C@@]2([#6])[#6]-3=[#6](-[#6]-[#6][C@]12[#6])[C@@]1([#6])[#6]-[#6]-[#6@H](-[#8])C([#6])([#6])[#6]1-[#6]-[#6]-3 |c:14|
Structure:
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