Target
Acyl carrier protein, mitochondrial
Ligand
BDBM50411903
Substrate
n/a
Meas. Tech.
ChEMBL_469770 (CHEMBL948046)
IC50
>25300±n/a nM
Citation
 Surup, FShojaei, Hvon Zezschwitz, PKunze, BGrond, S Iromycins from Streptomyces sp. and from synthesis: new inhibitors of the mitochondrial electron transport chain. Bioorg Med Chem 16:1738-46 (2008) [PubMed]  Article 
Target
Name:
Acyl carrier protein, mitochondrial
Synonyms:
ACP | ACPM_BOVIN | CI-SDAP | NADH-ubiquinone oxidoreductase 9.6 kDa subunit | NDUFAB1
Type:
PROTEIN
Mol. Mass.:
17397.64
Organism:
Bos taurus
Description:
ChEMBL_469770
Residue:
156
Sequence:
MAVRVLCACVRRLPTAFAPLPRLPTLAAARPLSTTLFAAETRTRPGAPLPALVLAQVPGRVTQLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
  
Inhibitor
Name:
BDBM50411903
Synonyms:
IROMYCIN E
Type:
Small organic molecule
Emp. Form.:
C19H29NO3
Mol. Mass.:
319.4385
SMILES:
CCCC1(O)C(=O)C(C)C(=O)N=C1C=CC(C)C\C=C\C(C)C |w:13.13,c:11|
Structure:
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