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Target
Neuropeptide FF receptor 2
Ligand
BDBM50414849
Substrate
n/a
Meas. Tech.
ChEMBL_590509 (CHEMBL1058556)
EC50
501.19±n/a nM
Citation
 Gaubert, G; Bertozzi, F; Kelly, NM; Pawlas, J; Scully, AL; Nash, NR; Gardell, LR; Lameh, J; Olsson, R Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists. J Med Chem 52:6511-4 (2009) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 2
Synonyms:
G-protein coupled receptor 74 | G-protein coupled receptor HLWAR77 | GPR74 | NPFF2 | NPFF2_HUMAN | NPFFR2 | NPGPR | Neuropeptide FF receptor 2 | Neuropeptide G-protein coupled receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
60293.78
Organism:
Homo sapiens (Human)
Description:
NPFF2 0 HUMAN::Q9Y5X5
Residue:
522
Sequence:
MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRRLGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
  
Inhibitor
Name:
BDBM50414849
Synonyms:
CHEMBL572766
Type:
Small organic molecule
Emp. Form.:
C9H10Cl2N4
Mol. Mass.:
245.109
SMILES:
[#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c1ccc(Cl)c(Cl)c1 |w:2.2|
Structure:
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