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Target
Androgen receptor
Ligand
BDBM50415098
Substrate
n/a
Meas. Tech.
ChEMBL_597011 (CHEMBL1041855)
EC50
15.85±n/a nM
Citation
 Schlienger, N; Lund, BW; Pawlas, J; Badalassi, F; Bertozzi, F; Lewinsky, R; Fejzic, A; Thygesen, MB; Tabatabaei, A; Bradley, SR; Gardell, LR; Piu, F; Olsson, R Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. J Med Chem 52:7186-91 (2009) [PubMed]  Article 
Target
Name:
Androgen receptor
Synonyms:
ANDR_MOUSE | Ar | Nr3c4
Type:
PROTEIN
Mol. Mass.:
98196.62
Organism:
Mus musculus
Description:
ChEMBL_945930
Residue:
899
Sequence:
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREAIQNPGPRHPEAANIAPPGACLQQRQETSPRRRRRQQHTEDGSPQAHIRGPTGYLALEEEQQPSQQQAASEGHPESSCLPEPGAATAPGKGLPQQPPAPPDQDDSAAPSTLSLLGPTFPGLSSCSADIKDILNEAGTMQLLQQQQQQQQHQQQHQQHQQQQEVISEGSSARAREATGAPSSSKDSYLGGNSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYASLLGGPPAVRPTPCAPLPECKGLPLDEGPGKSTEETAEYSSFKGGYAKGLEGESLGCSGSSEAGSSGTLEIPSSLSLYKSGALDEAAAYQNRDYYNFPLALSGPPHPPPPTHPHARIKLENPLDYGSAWAAAAAQCRYGDLGSLHGGSVAGPSTGSPPATTSSSWHTLFTAEEGQLYGPGGGGGSSSPSDAGPVAPYGYTRPPQGLTSQESDYSASEVWYPGGVVNRVPYPSPNCVKSEMGPWMENYSGPYGDMRLDSTRDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGENSNAGSPTEDPSQKMTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
  
Inhibitor
Name:
BDBM50415098
Synonyms:
CHEMBL570898
Type:
Small organic molecule
Emp. Form.:
C15H14N2
Mol. Mass.:
222.2851
SMILES:
N#Cc1ccc(N2CCCC2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: