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Target
Solute carrier family 22 member 2
Ligand
BDBM82070
Substrate
n/a
Meas. Tech.
ChEMBL_838729 (CHEMBL2078555)
Ki
50500±n/a nM
Citation
 Urakami, Y; Okuda, M; Masuda, S; Saito, H; Inui, KI Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs. J Pharmacol Exp Ther 287:800-5 (1998) [PubMed] 
Target
Name:
Solute carrier family 22 member 2
Synonyms:
Adrenaline alpha2 | Oct2 | Organic cation transporter 2 | S22A2_RAT | Slc22a2 | Solute carrier family 22 member 2 | rOCT2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
62348.38
Organism:
RAT
Description:
Adrenaline alpha2 0 RAT::Q9R0W2
Residue:
555
Sequence:
MSTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLGPCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCLLVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGICYQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGIITPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKEKRIYLQVKQADRPLS
  
Inhibitor
Name:
BDBM82070
Synonyms:
CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D salicylate | US10667515, Compound (S)-nicotine | US9303017, Nicotine
Type:
n/a
Emp. Form.:
C10H14N2
Mol. Mass.:
162.2316
SMILES:
CN1CCC[C@H]1c1cccnc1 |r|
Structure:
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