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Target
Solute carrier family 22 member 2
Ligand
BDBM50416487
Substrate
n/a
Meas. Tech.
ChEMBL_838484 (CHEMBL2076055)
IC50
5700±n/a nM
Citation
 Urakami, Y; Okuda, M; Masuda, S; Akazawa, M; Saito, H; Inui, K Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules. Pharm Res 18:1528-34 (2001) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 2
Synonyms:
Adrenaline alpha2 | Oct2 | Organic cation transporter 2 | S22A2_RAT | Slc22a2 | Solute carrier family 22 member 2 | rOCT2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
62348.38
Organism:
RAT
Description:
Adrenaline alpha2 0 RAT::Q9R0W2
Residue:
555
Sequence:
MSTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLGPCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCLLVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGICYQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGIITPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKEKRIYLQVKQADRPLS
  
Inhibitor
Name:
BDBM50416487
Synonyms:
CHEMBL1236196 | TETRABUTYLAMMONIUM
Type:
Small organic molecule
Emp. Form.:
C16H36N
Mol. Mass.:
242.4632
SMILES:
CCCC[N+](CCCC)(CCCC)CCCC
Structure:
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