Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 8
Ligand
BDBM50270006
Substrate
n/a
Meas. Tech.
ChEMBL_836314 (CHEMBL2076478)
Ki
1350000±n/a nM
Citation
 Hasegawa, M; Kusuhara, H; Sugiyama, D; Ito, K; Ueda, S; Endou, H; Sugiyama, Y Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. J Pharmacol Exp Ther 300:746-53 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 8
Synonyms:
Oat3 | Organic anion transporter 3 | S22A8_RAT | Slc22a8 | rOat3
Type:
PROTEIN
Mol. Mass.:
59199.83
Organism:
Rattus norvegicus
Description:
ChEMBL_1482580
Residue:
536
Sequence:
MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPWVLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNKLKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFRFLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQLTSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGTTALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG
  
Inhibitor
Name:
BDBM50270006
Synonyms:
2-(4-aminobenzamido)acetate | AMINOHIPPURATE
Type:
Small organic molecule
Emp. Form.:
C9H9N2O3
Mol. Mass.:
193.1799
SMILES:
Nc1ccc(cc1)C(=O)NCC([O-])=O
Structure:
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