Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 11
Ligand
BDBM50350468
Substrate
n/a
Meas. Tech.
ChEMBL_838708 (CHEMBL2078490)
Ki
1140±n/a nM
Citation
 Takeda, M; Babu, E; Narikawa, S; Endou, H Interaction of human organic anion transporters with various cephalosporin antibiotics. Eur J Pharmacol 438:137-42 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 11
Synonyms:
OAT4 | Organic anion transporter 4 | S22AB_HUMAN | SLC22A11
Type:
PROTEIN
Mol. Mass.:
59982.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_838708
Residue:
550
Sequence:
MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
  
Inhibitor
Name:
BDBM50350468
Synonyms:
CEFAMANDOLE
Type:
Small organic molecule
Emp. Form.:
C18H18N6O5S2
Mol. Mass.:
462.503
SMILES:
Cn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](O)c1ccccc1)C2=O)C(O)=O |r,t:9|
Structure:
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