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Target
Solute carrier organic anion transporter family member 2A1
Ligand
BDBM25902
Substrate
n/a
Meas. Tech.
ChEMBL_836139 (CHEMBL2077575)
Ki
47000±n/a nM
Citation
 Kanai, N; Lu, R; Satriano, JA; Bao, Y; Wolkoff, AW; Schuster, VL Identification and characterization of a prostaglandin transporter. Science 268:866-869 (1995) [PubMed]  Article 
Target
Name:
Solute carrier organic anion transporter family member 2A1
Synonyms:
Matr1 | Matrin F/G 1 | Prostaglandin transporter (PGT) | SO2A1_RAT | Slc21a2 | Slco2a1 | Solute carrier family 21 member 2
Type:
Protein
Mol. Mass.:
70404.97
Organism:
Rattus norvegicus (Rat)
Description:
Q00910
Residue:
644
Sequence:
MGLLLKPGARQGSGTSSVPDRRCPRSVFSNIKVFVLCHGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNATLIIFISYFGSRVNRPRMIGIGGLLLAAGAFVLTLPHFLSEPYQYTSTTDGNRSSFQTDLCQKHFGALPPSKCHSTVPDTHKETSSLWGLMVVAQLLAGIGTVPIQPFGISYVDDFAEPTNSPLYISILFAIAVFGPAFGYLLGSVMLRIFVDYGRVDTATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFFFFPRAMSRGAERSVTAEETMQTEEDKSRGSLMDFIKRFPRIFLRLLMNPLFMLVVLSQCTFSSVIAGLSTFLNKFLEKQYGATAAYANFLIGAVNLPAAALGMLFGGILMKRFVFPLQTIPRVAATIITISMILCVPLFFMGCSTSAVAEVYPPSTSSSIHPQQPPACRRDCSCPDSFFHPVCGDNGVEYVSPCHAGCSSTNTSSEASKEPIYLNCSCVSGGSASAKTGSCPTSCAQLLLPSIFLISFAALIACISHNPLYMMVLRVVNQDEKSFAIGVQFLLMRLLAWLPAPSLYGLLIDSSCVRWNYLCSGRRGACAYYDNDALRNRYLGLQMVYKALGTLLLFFISWRMKKNREYSLQENTSGLI
  
Inhibitor
Name:
BDBM25902
Synonyms:
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid | CHEMBL35 | Frusemide | Furanthril | Furosemide | Furosemide (3) | Furosemide, 4 | Lasix | US10172837, Furosemide
Type:
Small organic molecule
Emp. Form.:
C12H11ClN2O5S
Mol. Mass.:
330.744
SMILES:
NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl
Structure:
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