Reaction Details Report a problem with these data
Target
Solute carrier family 15 member 2
Ligand
BDBM50350474
Substrate
n/a
Meas. Tech.
ChEMBL_838253 (CHEMBL2076201)
Ki
44000±n/a nM
Citation
 Luckner, P; Brandsch, M Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. Eur J Pharm Biopharm 59:17-24 (2004) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 2
Synonyms:
Oligopeptide transporter, kidney isoform | Pept2 | S15A2_RAT | Slc15a2
Type:
PROTEIN
Mol. Mass.:
81331.63
Organism:
Rattus norvegicus
Description:
ChEMBL_838253
Residue:
729
Sequence:
MNPFQKNESKETLFSPVSTEEMLPRPPSPPKKSPPKIFGSSYPVSIAFIVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEEEHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVKCFGQDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPPEGNIVAQVIKCIWFALCNRFRNRSGDLPKRQHWLDWAAEKYPKHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLGFFVLQPDQMQVLNPFLVLIFIPLFDLVIYRLISKCRINFSSLRKMAVGMILACLAFAVAALVETKINGMIHPQPASQEIFLQVLNLADGDVKVTVLGSRNNSLLVESVSSFQNTTHYSKLHLEAKSQDLHFHLKYNSLSVHNDHSVEEKNCYQLLIHQDGESISSMLVKDTGIKPANGMAAIRFINTLHKDLNISLDTDAPLSVGKDYGVSAYRTVLRGKYPAVHCETEDKVFSLDLGQLDFGTTYLFVITNITSQGLQAWKAEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLVVAQFSGLAQWAEFVLFSCLLLVVCLIFSVMAYYYVPLKSEDTREATDKQIPAVQGNMINLETKNTRL
  
Inhibitor
Name:
BDBM50350474
Synonyms:
CICLACILLIN | CYCLACILLIN
Type:
Small organic molecule
Emp. Form.:
C15H23N3O4S
Mol. Mass.:
341.426
SMILES:
CC1(C)S[C@@H]2[C@H](NC(=O)C3(N)CCCCC3)C(=O)N2[C@H]1C(O)=O |r|
Structure:
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