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Target
Sex hormone-binding globulin
Ligand
BDBM50423500
Substrate
n/a
Meas. Tech.
ChEMBL_466706 (CHEMBL922711)
Kd
2188±n/a nM
Citation
 Cherkasov, A; Ban, F; Santos-Filho, O; Thorsteinson, N; Fallahi, M; Hammond, GL An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem 51:2047-56 (2008) [PubMed]  Article 
Target
Name:
Sex hormone-binding globulin
Synonyms:
SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein
Type:
PROTEIN
Mol. Mass.:
43780.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_466706
Residue:
402
Sequence:
MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSFCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
  
Inhibitor
Name:
BDBM50423500
Synonyms:
CHEMBL259997 | ZINC 00407192
Type:
Small organic molecule
Emp. Form.:
C18H16O3
Mol. Mass.:
280.3178
SMILES:
Cc1c(O)ccc2c(C)c(Cc3ccccc3)c(=O)oc12
Structure:
Search PDB for entries with ligand similarity: