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Target
Purine nucleoside phosphorylase
Ligand
BDBM50423778
Substrate
n/a
Meas. Tech.
ChEMBL_641938 (CHEMBL1176015)
Kd
79433±n/a nM
Citation
 Ducati, RG; Basso, LA; Santos, DS; de Azevedo, WF Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis. Bioorg Med Chem 18:4769-74 (2011) [PubMed]  Article 
Target
Name:
Purine nucleoside phosphorylase
Synonyms:
Inosine phosphorylase | Inosine-guanosine phosphorylase | MT3406 | PNP | PUNA_MYCTU | deoD | punA
Type:
PROTEIN
Mol. Mass.:
27567.15
Organism:
Mycobacterium tuberculosis
Description:
ChEMBL_641938
Residue:
268
Sequence:
MADPRPDPDELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHAGELLSVPIGAHRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQVGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALLADVIARF
  
Inhibitor
Name:
BDBM50423778
Synonyms:
Leukerin | MERCAPTOPURINE | Mercaleukin | Mercaptopurine anhydrous | Purinethol
Type:
Small organic molecule
Emp. Form.:
C5H4N4S
Mol. Mass.:
152.177
SMILES:
S=c1[nH]cnc2nc[nH]c12
Structure:
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