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Target
G protein-coupled receptor GPR35
Ligand
BDBM14363
Substrate
n/a
Meas. Tech.
ChEMBL_964307 (CHEMBL2395569)
EC50
61±n/a nM
Citation
 Funke, M; Thimm, D; Schiedel, AC; Müller, CE 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35. J Med Chem 56:5182-97 (2013) [PubMed]  Article 
Target
Name:
G protein-coupled receptor GPR35
Synonyms:
GPR35
Type:
PROTEIN
Mol. Mass.:
34295.07
Organism:
Rattus norvegicus
Description:
ChEMBL_107605
Residue:
306
Sequence:
MNNTNCSILPWPAAVNHIFTIYLVLLLVLGLLLNGLALWVFCYRMHQWTETRVYMTNLAVADVCLLCSLPFVLYSLKYSTSDTPICQLSQGIYLVNRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAGAVCVALWVIVVTSLVLRWRLGIQEGGFCFSSQNRYNFSTTAFSLLGFYLPLAIVVFCSLQVVTALARRPATDVEQVEATQKATRMVWANLAVFIICFLPLHLILTVQVSLNLHTCAARNIFSRALTITAKLSDINCCLDAICYYYMAKEFQDASLRATASSTPHKSQDTQSLSLT
  
Inhibitor
Name:
BDBM14363
Synonyms:
3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one | 5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | Tocris-0947 | Zaprinast
Type:
Small organic molecule
Emp. Form.:
C13H13N5O2
Mol. Mass.:
271.2746
SMILES:
CCCOc1ccccc1-c1nc2nn[nH]c2c(=O)[nH]1
Structure:
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