Reaction Details Report a problem with these data
Target
Oxoeicosanoid receptor 1
Ligand
BDBM50446960
Substrate
n/a
Meas. Tech.
ChEMBL_1290942 (CHEMBL3118915)
IC50
323±n/a nM
Citation
 Gore, V; Gravel, S; Cossette, C; Patel, P; Chourey, S; Ye, Q; Rokach, J; Powell, WS Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. J Med Chem 57:364-77 (2014) [PubMed]  Article 
Target
Name:
Oxoeicosanoid receptor 1
Synonyms:
5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45833.20
Organism:
Homo sapiens (Human)
Description:
TG 1019 0 HUMAN::Q8TDS5
Residue:
423
Sequence:
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
  
Inhibitor
Name:
BDBM50446960
Synonyms:
CHEMBL3115787
Type:
Small organic molecule
Emp. Form.:
C21H29NO4
Mol. Mass.:
359.4593
SMILES:
CCCCCCc1cc2ccc(OC)cc2n1C(=O)CC(C)CC(O)=O
Structure:
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