Reaction Details Report a problem with these data
Target
Diamine acetyltransferase 1
Ligand
BDBM45440
Substrate
n/a
Meas. Tech.
ChEMBL_1337637 (CHEMBL3242686)
Ki
2000±n/a nM
Citation
 Huang, TL; Mayence, A; Vanden Eynde, JJ Some non-conventional biomolecular targets for diamidines. A short survey. Bioorg Med Chem 22:1983-92 (2014) [PubMed]  Article 
Target
Name:
Diamine acetyltransferase 1
Synonyms:
SAT | SAT1 | SAT1_HUMAN | Spermidine/spermine N(1)-acetyltransferase 1
Type:
PROTEIN
Mol. Mass.:
20017.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1337637
Residue:
171
Sequence:
MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE
  
Inhibitor
Name:
BDBM45440
Synonyms:
4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydroxyethanesulfonic acid | 4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-hydroxyethanesulfonic acid | 4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;2-oxidanylethanesulfonic acid | CHEMBL494163 | MLS000028738 | PENTAMIDINE | PENTAMIDINE ISETHIONATE | SMR000059147 | cid_359323
Type:
Small organic molecule
Emp. Form.:
C19H24N4O2
Mol. Mass.:
340.4195
SMILES:
NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
Structure:
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