Target
GTP:AMP phosphotransferase AK3, mitochondrial
Ligand
BDBM50010314
Substrate
n/a
Meas. Tech.
ChEMBL_1340551 (CHEMBL3254975)
Ki
130000±n/a nM
Citation
 Hampton, APicker, D Design of species- or isozyme-specific enzyme inhibitors. 3. Species and isozymic differences between mammalian and bacterial adenylate kinases in substituent tolerance in an enzyme-substrate complex. J Med Chem 22:1529-32 (1980) [PubMed]  Article 
Target
Name:
GTP:AMP phosphotransferase AK3, mitochondrial
Synonyms:
AK 3 | Adenylate kinase 3 | Adenylate kinase 3 alpha like 1 | Adenylate kinase 3 alpha-like 1 | Ak3 | Ak3l1 | Akl3l | GTP:AMP phosphotransferase mitochondrial | KAD3_RAT
Type:
PROTEIN
Mol. Mass.:
25443.58
Organism:
Rattus norvegicus
Description:
ChEMBL_1340551
Residue:
227
Sequence:
MGASGRLLRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFIDQGKLIPDDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEALDRVYQIDTVINLNVPFEVIKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP
  
Inhibitor
Name:
BDBM50010314
Synonyms:
CHEMBL3251362
Type:
Small organic molecule
Emp. Form.:
C14H24N5O14P3S
Mol. Mass.:
611.352
SMILES:
Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(SCCCCO)nc12 |r|
Structure:
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