Target
Accessory gene regulator protein A
Ligand
BDBM50020379
Substrate
n/a
Meas. Tech.
ChEMBL_1366621 (CHEMBL3296715)
IC50
26500±n/a nM
Citation
 Figueroa, MJarmusch, AKRaja, HAEl-Elimat, TKavanaugh, JSHorswill, ARCooks, RGCech, NBOberlies, NH Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. J Nat Prod 77:1351-8 (2014) [PubMed]  Article 
Target
Name:
Accessory gene regulator protein A
Synonyms:
AGRA_STAAU | agr | agrA
Type:
PROTEIN
Mol. Mass.:
27903.57
Organism:
Staphylococcus aureus
Description:
ChEMBL_1366621
Residue:
238
Sequence:
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
  
Inhibitor
Name:
BDBM50020379
Synonyms:
CHEMBL3289788
Type:
Small organic molecule
Emp. Form.:
C17H14O7
Mol. Mass.:
330.2889
SMILES:
C[C@@H](O)[C@@H](O)c1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 |r|
Structure:
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